Erythropoietin processing in erythropoietic system and central nervous system

被引:9
作者
Nagao, M
Masuda, S
Ueda, M
Sasaki, R
机构
[1] KYOTO UNIV,FAC AGR,DEPT FOOD SCI & TECHNOL,KYOTO 606,JAPAN
[2] SNOW BRAND MILK PROD CO LTD,LIFE SCI RES INST,ISHIBASHI,TOCHIGI 32905,JAPAN
关键词
erythropoietin; glycosylation; erythropoiesis; central nervous system;
D O I
10.1007/BF00744323
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We describe possible functions of carbohydrates attached to growth factors and strategies to examine the functions, concentrating on erythropoietin, a major regulator of erythropoiesis. Erythropoietin in erythropoiesis functions as an endocrine hormone; it is produced by kidney cells and transferred into the circulation to hemopoietic sites. In the brain, erythropoietin acts on neurons in a paracrine fashion. Comparison of glycosylation has been made between kidney and brain erythropoietins.
引用
收藏
页码:83 / 91
页数:9
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