IMMOBILIZATION OF RHODIUM COMPLEXES IN AQUEOUS HBF4 - THE ENANTIOSELECTIVE HYDROGENATION OF PROCHIRAL OLEFINS WITH ([CH3CHP(PARA-C6H4NME2H)2CH2CHP(PARA-C6H4NME2H)2CH3]RHNBD)5+

被引：34

作者：

TOTH, I

HANSON, BE

DAVIS, ME

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV,DEPT CHEM,BLACKSBURG,VA 24061

[2] VIRGINIA POLYTECH INST & STATE UNIV,DEPT CHEM ENGN,BLACKSBURG,VA 24061

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1990年 / 396卷 / 2-3期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0022-328X(90)85477-G

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The complex {[CH3CHP(p-C6H4NMe2H)2CH2CHP(p-C6H4NMe2H)2CH3]RhNBD}5+ is active for the enantioselective hydrogenation of cinnamic acid derivatives at low pH in aqueous solutions of the noncoordinating acid HBF4. Analytical data are consistent with protonation occurring exclusively at the dimethylamino groups and not at the metal. Enantiomeric excesses of 67 to 97% are obtained for the hydrogenation of Z-(4-OMe, 3-OAcC6H3CHC(NHC(O)Me)COOH in aqueous HBF4 at 14 bar H2. The use of aqueous acidic solutions allows for the convenient workup of the product and recycling of the catalyst. © 1990.

引用

页码：363 / 373

页数：11

共 35 条

[1] ASYMMETRIC HYDROGENATION IN AQUEOUS ORGANIC 2-PHASE SOLVENT SYSTEMS USING RHODIUM COMPLEXES OF SULFONATED PHOSPHINES [J].