NITROACRIDINES WITH SELECTIVE TOXICITY TOWARDS HYPOXIC MAMMALIAN-CELLS - SYNTHESIS AND STABILITY OF TRITIATED DERIVATIVES

被引：10

作者：

DENNY, WA ^{[1
]}

CHAMBERS, D ^{[1
]}

STEWART, GM ^{[1
]}

WILSON, WR ^{[1
]}

机构：

[1] UNIV AUCKLAND,SCH MED,DEPT PATHOL,ONCOL SECT,AUCKLAND,NEW ZEALAND

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 1985年 / 22卷 / 10期

关键词：

D O I：

10.1002/jlcr.2580221003

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：995 / 1005

页数：11

共 13 条

[1]

Albert A., 1966, ACRIDINES

[2]

GNIAZDOWSKI M, 1979, ANTIBIOTICS 2, V5

[3] HYPOXIC TUMOR-CELL - TARGET FOR SELECTIVE CANCER-CHEMOTHERAPY [J].

KENNEDY, KA ;

TEICHER, BA ;

ROCKWELL, S ;

SARTORELLI, AC .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (01) :1-8

[4] SYNTHESIS OF A TUMOR GROWTH-INHIBITOR DIHYDROCHLORIDE OF 1-NITRO-9--DIMETHYLAMINO-PROPYLAMINO--ACRIDINE C-283 TRITIUM LABELED IN ACRIDINE RING AND C-14-LABELED IN SIDE-CHAIN [J].

KOLODZIEJCZYK, A ;

ARENDT, A .

JOURNAL OF LABELLED COMPOUNDS, 1975, 11 (03) :385-394

[5] THE MODE OF ACTION OF CYTO-TOXIC AND ANTI-TUMOR 1-NITROACRIDINES .3. INVIVO INTERSTRAND CROSS-LINKING OF DNA OF MAMMALIAN OR BACTERIAL-CELLS BY 1-NITROACRIDINES [J].

KONOPA, J ;

PAWLAK, JW ;

PAWLAK, K .

CHEMICO-BIOLOGICAL INTERACTIONS, 1983, 43 (02) :175-197

[6]

KWASNIEWSKAROKI.C, 1969, ARCH IMMUNOL THER EX, V17, P376

[7]

LEDOCHOWSKI A, 1974, ROCZ CHEM, V48, P933

[8]

LEDOCHOWSKI A, 1966, ROCZN CHEM, V40, P301

[9] THE MODE OF ACTION OF CYTO-TOXIC AND ANTI-TUMOR 1-NITROACRIDINES .1. THE 1-NITROACRIDINES DO NOT EXERT THEIR CYTO-TOXIC EFFECTS BY PHYSICOCHEMICAL BINDING WITH DNA [J].

PAWLAK, K ;

MATUSZKIEWICZ, A ;

PAWLAK, JW ;

KONOPA, J .

CHEMICO-BIOLOGICAL INTERACTIONS, 1983, 43 (02) :131-149

[10]

RADZIKOWSKI CZESLAW, 1967, ARCH IMMUNOL THERAP EXP, V15, P126

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