A NOVEL METHOD FOR THE SYNTHESIS OF ISOCYANATES UNDER MILD CONDITIONS

被引：148

作者：

KNOLKER, HJ

BRAXMEIER, T

SCHLECHTINGEN, G

机构：

[1] Institut für Organische Chemie, Universität Karlsruhe, D-76131, Richard‐Willstätter‐Allee

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 22期

关键词：

ARENES; DI-TERT-BUTYL DICARBONATE; ISOCYANATES;

D O I：

10.1002/anie.199524971

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Not the amine‐N‐Boc derivatives, but the isocyanates form in the reaction of alkyl‐ or arylamines with di‐tert‐butyl dicarbonate ((Boc)2O) in the presence of a catalytic amount of 4‐dimethylaminopyridine (DMAP) according to Equation (a). The procedure provides a simple laboratory method of generating sterically hindered alkyl and aryl isocyanates without the use of phosgene. (Formula Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：2497 / 2500

页数：4

共 17 条

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