THE SYNTHESIS OF OLIGODEOXYNUCLEOTIDES CONTAINING 4-THIOTHYMIDINE RESIDUES

被引:30
作者
NIKIFOROV, TT [1 ]
CONNOLLY, BA [1 ]
机构
[1] UNIV SOUTHAMPTON,DEPT BIOCHEM,SERC,MOLEC RECOGNIT INITIAT CTR,SOUTHAMPTON SO9 3TU,HANTS,ENGLAND
关键词
D O I
10.1016/S0040-4039(00)79395-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Oligodeoxynucleotides containing 4-thiothymidine residues were obtained using the phosphoramidites of 2 and 3. Treatment with CH3COSK in EtOH was used to introduce the 4-thioketo function at the oligodeoxynucleotide level.
引用
收藏
页码:3851 / 3854
页数:4
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