CHARACTERIZATION OF 3 VNTR SYSTEMS AT D21S112

被引：2

作者：

TAKAESU, N

NEWFELD, S

HASSOLD, T

机构：

[1] EMORY UNIV,SCH MED,DEPT PEDIAT,DIV MED GENET,ATLANTA,GA 30322

[2] EMORY UNIV,SCH MED,DEPT BIOL,ATLANTA,GA 30322

来源：

GENOMICS | 1992年 / 14卷 / 03期

关键词：

D O I：

10.1016/S0888-7543(05)80197-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

D21S112 is a highly polymorphic marker on the long arm of chromosome 21. Our analysis of this locus indicated the presence of three VNTR systems. We estimated the heterozygosity of each system and sequenced one of the repetitive regions. Utilizing PCR, we demonstrated that the sequenced VNTR is responsible for the system with the highest level of heterozygosity. Combining data from the three systems makes D21S112 one of the most informative loci on the chromosome. © 1992 Academic Press, Inc. All rights reserved.

引用

页码：816 / 817

页数：2

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