FORMATION AND RETENTION AND BIOLOGICAL-ACTIVITY OF N10-PROPARGYL-5,8-DIDEAZAFOLIC ACID (CB3717) POLYGLUTAMATES IN L1210 CELLS-INVITRO

被引：82

作者：

SIKORA, E ^{[1
]}

JACKMAN, AL ^{[1
]}

NEWELL, DR ^{[1
]}

CALVERT, AH ^{[1
]}

机构：

[1] INST CANC RES, DRUG DEV SECT, CLIN PHARMACOL TEAM, SUTTON SM2 5PX, SURREY, ENGLAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1988年 / 37卷 / 21期

关键词：

D O I：

10.1016/0006-2952(88)90094-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：4047 / 4054

页数：8

共 52 条

[1] INHIBITION OF PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE TRANSFORMYLASE BY METHOTREXATE AND DIHYDROFOLIC ACID POLYGLUTAMATES
ALLEGRA, CJ
DRAKE, JC
JOLIVET, J
CHABNER, BA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (15) : 4881 - 4885
[2] ALLEGRA CJ, 1985, J BIOL CHEM, V260, P9720
[3] POLYGAMMAGLUTAMYL METABOLITES OF METHOTREXATE
BAUGH, CM
KRUMDIECK, CL
NAIR, MG
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1973, 52 (01) : 27 - 34
[4] Calvert A H, 1987, NCI Monogr, P213
[5] A PHASE-I EVALUATION OF THE QUINAZOLINE ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITOR, N-10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, CB3717
CALVERT, AH
ALISON, DL
HARLAND, SJ
ROBINSON, BA
JACKMAN, AL
JONES, TR
NEWELL, DR
SIDDIK, ZH
WILTSHAW, E
MCELWAIN, TJ
SMITH, IE
HARRAP, KR
[J]. JOURNAL OF CLINICAL ONCOLOGY, 1986, 4 (08) : 1245 - 1252
[6] QUINAZOLINE ANTIFOLATES WITH DUAL BIOCHEMICAL LOCI OF ACTION - BIOCHEMICAL AND BIOLOGICAL STUDIES DIRECTED TOWARDS OVERCOMING METHOTREXATE RESISTANCE
CALVERT, AH
JONES, TR
DADY, PJ
GRZELAKOWSKASZTABERT, B
PAINE, RM
TAYLOR, GA
HARRAP, KR
[J]. EUROPEAN JOURNAL OF CANCER, 1980, 16 (05) : 713 - 722
[7] POLYGLUTAMATION OF METHOTREXATE - IS METHOTREXATE A PRODRUG
CHABNER, BA
ALLEGRA, CJ
CURT, GA
CLENDENINN, NJ
BARAM, J
KOIZUMI, S
DRAKE, JC
JOLIVET, J
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1985, 76 (03) : 907 - 912
[8] CHENG YC, 1985, CANCER RES, V45, P598
[9] COWAN KH, 1984, J BIOL CHEM, V259, P793
[10] DIDDENS H, 1983, CANCER RES, V43, P5286

← 1 2 3 4 5 6 →