ASCORBIC-ACID STIMULATES COLLAGEN PRODUCTION WITHOUT ALTERING INTRACELLULAR DEGRADATION IN CULTURED HUMAN-SKIN FIBROBLASTS

被引：19

作者：

GEESIN, J ^{[1
]}

MURAD, S ^{[1
]}

PINNELL, SR ^{[1
]}

机构：

[1] DUKE UNIV,MED CTR,DEPT MED,DIV DERMATOL,DURHAM,NC 27710

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1986年 / 886卷 / 02期

关键词：

D O I：

10.1016/0167-4889(86)90145-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：272 / 274

页数：3

共 15 条

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[6] SPECIFICALLY DECREASED COLLAGEN BIOSYNTHESIS IN SCURVY DISSOCIATED FROM AN EFFECT ON PROLINE HYDROXYLATION AND CORRELATED WITH BODY-WEIGHT LOSS - INVITRO STUDIES IN GUINEA-PIG CALVARIAL BONES [J].

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[7]

GEESIN JC, 1985, CLIN RES, V33, pA639

[8] ASCORBATE STIMULATION OF PAT CELLS CAUSES AN INCREASE IN TRANSCRIPTION RATES AND A DECREASE IN DEGRADATION RATES OF PROCOLLAGEN MESSENGER-RNA [J].

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[9] AN INTRAMEMBRANOUS REDUCTANT WHICH PARTICIPATES IN THE PROLINE HYDROXYLATION REACTION WITH INTRACISTERNAL PROLYL HYDROXYLASE AND UNHYDROXYLATED PROCOLLAGEN IN ISOLATED MICROSOMES FROM L-929 CELLS [J].

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[10] REGULATION OF COLLAGEN-SYNTHESIS BY ASCORBIC-ACID [J].

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