CLONING THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX IN YACS

被引：43

作者：

ABDERRAHIM, H ^{[1
]}

SAMBUCY, JL ^{[1
]}

IRIS, F ^{[1
]}

OUGEN, P ^{[1
]}

BILLAULT, A ^{[1
]}

CHUMAKOV, IM ^{[1
]}

DAUSSET, J ^{[1
]}

COHEN, D ^{[1
]}

LEPASLIER, D ^{[1
]}

机构：

[1] CTR ETUD POLYMORPHISME HUMAIN,FDN JEAN DAUSSET,F-75010 PARIS,FRANCE

来源：

GENOMICS | 1994年 / 23卷 / 03期

关键词：

D O I：

10.1006/geno.1994.1538

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

To clone the human major histocompatibility complex (MHC), 53 YACs, with an average size of 490 kb, were isolated and characterized from the CEPH YAC library. These YACs were organized in a single large contig covering more than 4000 kb. Furthermore, a complete physical map of the previously uncloned HLA class I region was established from partial and/or total digestions of 15 YACs spanning 2000 kb. This resulted in the establishment of the first YAC contig that spans the entire MHC region and constitutes an essential step in the isolation of all of the genes present in the region. (C) 1994 Academic Press, Inc.

引用

页码：520 / 527

页数：8

共 43 条

[1] CONSTRUCTION AND CHARACTERIZATION OF A YEAST ARTIFICIAL CHROMOSOME LIBRARY CONTAINING 7 HAPLOID HUMAN GENOME EQUIVALENTS
ALBERTSEN, HM
ABDERRAHIM, H
CANN, HM
DAUSSET, J
LEPASLIER, D
COHEN, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (11) : 4256 - 4260
[2] ISOLATION AND CHARACTERIZATION OF YEAST ARTIFICIAL CHROMOSOME CLONES LINKING THE HLA-B AND HLA-C LOCI
BRONSON, SK
PEI, J
TAILLONMILLER, P
CHORNEY, MJ
GERAGHTY, DE
CHAPLIN, DD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (05) : 1676 - 1680
[3] ISOLATION OF SINGLE-COPY HUMAN GENES FROM A LIBRARY OF YEAST ARTIFICIAL CHROMOSOME CLONES
BROWNSTEIN, BH
SILVERMAN, GA
LITTLE, RD
BURKE, DT
KORSMEYER, SJ
SCHLESSINGER, D
OLSON, MV
[J]. SCIENCE, 1989, 244 (4910) : 1348 - 1351
[4] CLONING OF LARGE SEGMENTS OF EXOGENOUS DNA INTO YEAST BY MEANS OF ARTIFICIAL CHROMOSOME VECTORS
BURKE, DT
CARLE, GF
OLSON, MV
[J]. SCIENCE, 1987, 236 (4803) : 806 - 812
[5] ELECTROPHORETIC SEPARATIONS OF LARGE DNA-MOLECULES BY PERIODIC INVERSION OF THE ELECTRIC-FIELD
CARLE, GF
FRANK, M
OLSON, MV
[J]. SCIENCE, 1986, 232 (4746) : 65 - 68
[6] LINKAGE MAP OF THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX INCLUDING THE TUMOR-NECROSIS-FACTOR GENES
CARROLL, MC
KATZMAN, P
ALICOT, EM
KOLLER, BH
GERAGHTY, DE
ORR, HT
STROMINGER, JL
SPIES, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (23) : 8535 - 8539
[7] MAPPING OF STEROID 21-HYDROXYLASE GENES ADJACENT TO COMPLEMENT COMPONENT C-4 GENES IN HLA, THE MAJOR HISTOCOMPATIBILITY COMPLEX IN MAN
CARROLL, MC
CAMPBELL, RD
PORTER, RR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (02) : 521 - 525
[8] TRANSCRIPTION ANALYSIS, PHYSICAL MAPPING, AND MOLECULAR CHARACTERIZATION OF A NONCLASSICAL HUMAN-LEUKOCYTE ANTIGEN CLASS-I GENE
CHORNEY, MJ
SAWADA, I
GILLESPIE, GA
SRIVASTAVA, R
PAN, J
WEISSMAN, SM
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (01) : 243 - 253
[9] SEPARATION OF LARGE DNA-MOLECULES BY CONTOUR-CLAMPED HOMOGENEOUS ELECTRIC-FIELDS
CHU, G
VOLLRATH, D
DAVIS, RW
[J]. SCIENCE, 1986, 234 (4783) : 1582 - 1585
[10] ISOLATION OF CHROMOSOME-21-SPECIFIC YEAST ARTIFICIAL CHROMOSOMES FROM A TOTAL HUMAN GENOME LIBRARY
CHUMAKOV, IM
LEGALL, I
BILLAULT, A
OUGEN, P
SOULARUE, P
GUILLOU, S
RIGAULT, P
BUI, H
DETAND, MF
BARILLOT, E
ABDERRAHIM, H
CHERIF, D
BERGER, R
LEPASLIER, D
COHEN, D
[J]. NATURE GENETICS, 1992, 1 (03) : 222 - 225

← 1 2 3 4 5 →