CHEMOSELECTIVE ENZYMATIC-HYDROLYSIS OF ALIPHATIC AND ALICYCLIC NITRILES

被引：41

作者：

DERAADT, A ^{[1
]}

KLEMPIER, N ^{[1
]}

FABER, K ^{[1
]}

GRIENGL, H ^{[1
]}

机构：

[1] GRAZ UNIV TECHNOL, INST ORGAN CHEM, CHRISTIAN DOPPLER LAB CHEM CHIRAL CPDS, A-8010 GRAZ, AUSTRIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 01期

关键词：

D O I：

10.1039/p19920000137

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mild and selective hydrolysis of aliphatic and alicyclic nitriles leading to carboxylic acids and amides was achieved under neutral conditions by an immobilized enzyme preparation from Rhodococcus sp. This method is particularly useful for the transformation of compounds containing other acid- or base-sensitive groups.

引用

页码：137 / 140

页数：4

共 39 条

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