MALIGNANT PROLACTINOMA

被引：12

作者：

BEREZIN, M

GUTMAN, I

TADMOR, R

HOROWITZ, A

FINDLER, G

机构：

[1] CHAIM SHEBA MED CTR,DEPT PATHOL,IL-52621 TEL HASHOMER,ISRAEL

[2] CHAIM SHEBA MED CTR,DEPT NEUROSURG,IL-52621 TEL HASHOMER,ISRAEL

[3] CHAIM SHEBA MED CTR,INST OPHTHALMOL,NEUROOPHTHALMOL UNIT,IL-52621 TEL HASHOMER,ISRAEL

[4] CHAIM SHEBA MED CTR,INST RADIOL,NEURORADIOL UNIT,IL-52621 TEL HASHOMER,ISRAEL

来源：

ACTA ENDOCRINOLOGICA | 1992年 / 127卷 / 05期

关键词：

D O I：

10.1530/acta.0.1270476

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Malignant prolactinoma is a rare entity and only a few cases have been published. The diagnostic criteria and the clinical course remain unclear. We present a case of malignant prolactinoma in a woman with a 30-year duration of the disease. In the terminal stage of the disease the prolactinoma metastasized to the left eye, the prolactin level reaching 1 96000 mU/l. Bromocriptine in high doses was not effective. The response to pergolide was good in the first two years of treatment; thereafter an escape effect was observed. The patient died in a comatose state. A review of previously published cases follows.

引用

页码：476 / 480

页数：5

共 25 条

[1]

ASSIES J, 1991, Journal of Endocrinological Investigation, V14, P208

[2]

BAILY QT, 1940, ARCH PATH, V29, P336

[3] AN INTRACRANIAL METASTASIS FROM A PRL SECRETING PITUITARY-TUMOR [J].