Association between inflammatory bowel disease and sarcoidosis - Report of two cases and review of the literature

被引:40
作者
Fries, W [1 ]
Grassi, SA [1 ]
Leone, L [1 ]
Giacomin, D [1 ]
Galeazzi, F [1 ]
Naccarato, R [1 ]
Martin, A [1 ]
机构
[1] OC MAROSTICA,DIV MED,VICENZA,ITALY
关键词
inflammatory bowel disease; sarcoidosis;
D O I
10.3109/00365529509101635
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: Common etiopathogenic factors may explain the association of systemic sarcoidosis with inflammatory bowel disease. Methods: We report two cases of such an association: one of sarcoidosis that developed 2 years after proctocolectomy for ulcerative colitis and one of sarcoidosis and Crohn's colitis. Factors like increased cellular immunity or circulating immunocomplexes or autoantibodies may have a role. Exogenous agents or familiarity may also be involved. Conclusions: It is postulated that the association between sarcoidosis and inflammatory bowel disease (both ulcerative colitis and Crohn's disease) does not occur by chance alone and that the two conditions may share some genetic or immunologic alterations. The two diseases, however, follow an independent clinical course.
引用
收藏
页码:1221 / 1223
页数:3
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