NI(0)-CATALYZED CROSS COUPLING OF ARYL O-CARBAMATES AND ARYL TRIFLATES WITH GRIGNARD-REAGENTS - DIRECTED ORTHOMETALLATION-ALIGNED SYNTHETIC METHODS FOR POLYSUBSTITUTED AROMATICS VIA A 1,2-DIPOLE EQUIVALENT

被引：167

作者：

SENGUPTA, S ^{[1
]}

LEITE, M ^{[1
]}

RASLAN, DS ^{[1
]}

QUESNELLE, C ^{[1
]}

SNIECKUS, V ^{[1
]}

机构：

[1] UNIV FED MINAS GERAIS,BR-30000 BELO HORIZONT,MG,BRAZIL

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 15期

关键词：

D O I：

10.1021/jo00041a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first Ni(0)-catalyzed cross-coupling reactions of aryl O-carbamates and aryl triflates with Grignard reagents (Scheme I) to give diversely polysubstituted aromatics 2d and 2e (Table I) which feature regiospecificity based on directed ortho metalation (carbamate), minimal beta-hydride elimination (triflate), and dependence on steric and electronic effects are described.

引用

页码：4066 / 4068

页数：3

共 27 条

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