SPONTANEOUS FIRING OF NIGROSTRIATAL DOPAMINERGIC-NEURONS IN SPLIT-BRAIN RATS

被引：14

作者：

CASTELLANO, MA ^{[1
]}

RIVERO, FL ^{[1
]}

RODRIGUEZ, M ^{[1
]}

机构：

[1] UNIV LA LAGUNA,FAC MED,DEPT FISIOL,CANARY ISL,SPAIN

来源：

NEUROSCIENCE LETTERS | 1993年 / 162卷 / 1-2期

关键词：

NIGROSTRIATAL DOPAMINERGIC NEURON; FIRING PATTERN; BURSTING ACTIVITY; CONTRALATERAL REGULATION; SPLIT-BRAIN; SINGLE-UNIT RECORDING;

D O I：

10.1016/0304-3940(93)90545-V

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The regulatory action of the contralateral brain side on nigrostriatal dopaminergic (NSDA) neurons was examined in anesthetized rats using extraoellular single-unit recording techniques. The spontaneous activity of NSDA cells was recorded from split-brain, sham-lesioned or intact-brain rats. The three groups of cells did not differ in antidromic latency and firing rate. However, cells from split-brain rats exhibited a more regular pattern of discharge than those recorded in the two control groups as shown by autocorrelograms and the standard deviation and variation coefficient of the interspike intervals. In addition, burst firing was found to be markedly reduced in the split-brain group. It is concluded that decussating pathways are involved in the regulation of the discharge pattern of NSDA neurons.

引用

页码：1 / 4

页数：4

共 28 条

[1] CHOLECYSTOKININ POTENTIATES DOPAMINE-INHIBITION OF MESENCEPHALIC DOPAMINE NEURONS INVITRO [J].