METABOLIC RESISTANCE TO TIGHT-BINDING INHIBITORS OF ENZYMES INVOLVED IN THE DENOVO PYRIMIDINE PATHWAY - SIMULATION OF TIME-DEPENDENT EFFECTS

被引：10

作者：

DUGGLEBY, RG ^{[1
]}

CHRISTOPHERSON, RI ^{[1
]}

机构：

[1] UNIV MELBOURNE,DEPT BIOCHEM,PARKVILLE,VIC 3052,AUSTRALIA

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1984年 / 143卷 / 01期

关键词：

D O I：

10.1111/j.1432-1033.1984.tb08362.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：221 / 226

页数：6

共 31 条

[1]

Agarwal R P, 1978, Methods Enzymol, V51, P376

[2]

BJURSELL G, 1973, J BIOL CHEM, V248, P3904

[3] PROGRAM FOR EFFICIENT INTEGRATION OF RATE EQUATIONS AND LEAST-SQUARES FITTING OF CHEMICAL REACTION DATA [J].

CHANDLER, JP ;

SPIVEY, HO ;

HILL, DE .

COMPUTERS AND BIOMEDICAL RESEARCH, 1972, 5 (05) :515-&

[4] METABOLIC RESISTANCE - THE PROTECTION OF ENZYMES AGAINST DRUGS WHICH ARE TIGHT-BINDING INHIBITORS BY THE ACCUMULATION OF SUBSTRATE [J].

CHRISTOPHERSON, RI ;

DUGGLEBY, RG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1983, 134 (02) :331-335

[5]

CHRISTOPHERSON RI, 1980, J BIOL CHEM, V255

[6]

COLEMAN PF, 1977, J BIOL CHEM, V252, P6379

[7]

CORY JG, 1975, CANCER RES, V35, P390

[8] ALLOSTERIC REGULATION OF CALF THYMUS RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE [J].

ERIKSSON, S ;

THELANDER, L ;

AKERMAN, M .

BIOCHEMISTRY, 1979, 18 (14) :2948-2952

[9]

HITCHINGS GH, 1973, ADV ENZYME REGUL, V12, P121

[10]

HOWELL SB, 1980, CANCER RES, V40, P1824

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