THE BENZOSTABASE PROTECTING GROUP FOR PRIMARY AMINES - APPLICATION TO ALIPHATIC-AMINES

被引：30

作者：

BONARLAW, RP

DAVIS, AP

DORGAN, BJ

REETZ, MT

WEHRSIG, A

机构：

[1] UNIV DUBLIN TRINITY COLL,DEPT CHEM,DUBLIN 2,IRELAND

[2] UNIV MARBURG,FACHBEREICH CHEM,W-3550 MARBURG,GERMANY

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)97158-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The "benzostabase" (BSB) protecting group has been applied to primary aliphatic amines. It can be introduced via a dehydrogenative silylation employing an air- and moisture-stable reagent, and is appreciably more acid-stable than the related "stabase" group. BSB protection has been used in a stereoselective synthesis of amino-alcohols involving the addition of organometallic reagents to protected amino-aldehydes under "non-chelation control". © 1990.

引用

页码：6725 / 6728

页数：4

共 8 条

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