STEREOSELECTIVE ANALYSIS OF THE ENANTIOMERS OF MEXILETINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY USING FLUORESCENCE DETECTION AND STUDY OF THEIR STEREOSELECTIVE DISPOSITION IN MAN

被引：50

作者：

MCERLANE, KM ^{[1
]}

IGWEMEZIE, L ^{[1
]}

KERR, CR ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,FAC MED,VANCOUVER V6T 1W5,BC,CANADA

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1987年 / 415卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)83225-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：335 / 346

页数：12

共 18 条

[1] DETERMINATION OF MEXILETINE AND ITS METABOLITES IN SERUM BY LIQUID-CHROMATOGRAPHY WITH FLUORESCENCE DETECTION [J].

FARID, NA ;

WHITE, SM .

JOURNAL OF CHROMATOGRAPHY, 1983, 275 (02) :458-462

[2] NEW ELECTRON-CAPTURE GAS-LIQUID-CHROMATOGRAPHIC METHOD FOR DETERMINATION OF MEXILETINE PLASMA-LEVELS IN MAN [J].

FRYDMAN, A ;

LAFARGE, JP ;

VIAL, F ;

RULLIERE, R ;

ALEXANDRE, JM .

JOURNAL OF CHROMATOGRAPHY, 1978, 145 (03) :401-411

[3] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ASSAY FOR MEXILETINE ENANTIOMERS IN HUMAN-PLASMA [J].

GRECHBELANGER, O ;

TURGEON, J ;

GILBERT, M .

JOURNAL OF CHROMATOGRAPHY, 1985, 337 (01) :172-177

[4] HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC ASSAY FOR MEXILETINE IN SERUM [J].

GRECHBELANGER, O ;

TURGEON, J ;

GILBERT, M .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1984, 22 (11) :490-492

[5] SIMPLE GAS-LIQUID-CHROMATOGRAPHIC METHOD FOR THE MEASUREMENT OF MEXILETINE AND LIGNOCAINE IN BLOOD-PLASMA OR SERUM [J].

HOLT, DW ;

FLANAGAN, RJ ;

HAYLER, AM ;

LOIZOU, M .

JOURNAL OF CHROMATOGRAPHY, 1979, 169 (FEB) :295-301

[6] MEXILETINE IN PLASMA BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY [J].

KELLY, R ;

CHRISTMORE, D ;

SMITH, R ;

DOSHIER, L ;

JACOBS, SL .

THERAPEUTIC DRUG MONITORING, 1981, 3 (03) :279-286

[7] CHIRAL STATIONARY PHASES FOR THE GAS-LIQUID CHROMATOGRAPHIC-SEPARATION OF ENANTIOMERS [J].

LIU, RH ;

KU, WW .

JOURNAL OF CHROMATOGRAPHY, 1983, 271 (03) :309-323

[8] CHROMATOGRAPHIC-SEPARATION OF THE ENANTIOMERS OF ACYLATED AMINES ON CHIRAL STATIONARY PHASES [J].

PIRKLE, WH ;

WELCH, CJ .

JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (01) :138-140

[9]

PRESCOTT LF, 1977, POSTGRAD MED J, V53, P50

[10]

SEDMAN AJ, 1976, AUTOAN

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