A 4-YEAR FOLLOW-UP-STUDY ON THE INCIDENCE OF DIABETIC-RETINOPATHY IN OLDER ONSET DIABETES-MELLITUS

被引：33

作者：

AGARDH, E

AGARDH, CD

KOUL, S

TORFFVIT, O

机构：

[1] Departments of Ophthalmology, University Hospital, Lund

[2] Departments of Internal Medicine, University Hospital, Lund

来源：

DIABETIC MEDICINE | 1994年 / 11卷 / 03期

关键词：

DIABETES-MELLITUS; RETINOPATHY; INCIDENCE; HYPERTENSION; NEPHROPATHY; METABOLIC CONTROL; HBA(1C); INSULIN;

D O I：

10.1111/j.1464-5491.1994.tb00271.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Out of 369 diabetic patients with an age at onset of diabetes greater-than-or-equal-to 30 years previously studied, 325 (88 %) were included in an ophthalmological follow-up examination 4 years later. In patients treated with oral drugs at baseline, the incidence of any type of retinopathy was 30.8 % and of severe retinopathy 5.7 %. All patients who developed severe retinopathy received insulin during the follow-up period. At baseline, duration of diabetes, diastolic blood pressure, and signs of nephropathy (p < 0.05 in all cases) as well as degree of metabolic control (p < 0.01) differed between patients who developed retinopathy and those who did not. At follow-up, there were no longer any differences regarding degree of metabolic control and diastolic blood pressure. In patients treated with insulin at baseline, the incidence of any type of retinopathy was 41.0 % and of severe retinopathy 16.1 %. At baseline, duration of diabetes (p < 0.01), degree of metabolic control, and insulin dosage (p < 0.05 in both cases) differed between patients who developed retinopathy and those who did not. At follow-up, there was no longer any difference in insulin dosage.

引用

页码：273 / 278

页数：6

共 16 条

[1]

Dwyer MS, Melton LJ, Ballard DJ, Palumbo PJ, Trautmann JC, Chu C-P., Incidence of diabetic retinopathy and blindness: a population‐based study in Rochester, Minnesota, Diabetes Care, 8, pp. 316-322, (1985)

[2]

Lawson PM, Hunt B., Kohner EM., Medical conditions in patients with diabetic maculopathy, Diabetic Med, 2, pp. 245-250, (1985)

[3]

Moss SE, Klein R., Klein BEK., The incidence of vision loss in a diabetic population, Ophthalmology, 95, pp. 1340-1348, (1988)

[4]

Nielsen NV., Diabetic retinopathy I. The course of retinopathy in insulin‐treated diabetics. A one‐year epidemiological cohort study of diabetes mellitus. The Island of Falster, Denmark, Acta Ophthalmol, 62, pp. 256-265, (1984)

[5]

Nielsen NV., Diabetic retinopathy II. The course of retinopathy in diabetics treated with oral hypoglycaemic agents and diet regime alone. A one‐year epidemiological cohort study of diabetes mellitus. The Island of Falster, Denmark, Acta Ophthalmol, 62, pp. 266-273, (1984)

[6]

Early photocoagulation for diabetic retinopathy, Ophthalmology, 98, pp. 766-785, (1991)

[7]

Agardh E., Agardh C-D, Hansson-Lundblad C., The five‐year incidence of blindness after introducing a screening programme for early detection of treatable diabetic retinopathy, Diabetic Med, 10, pp. 555-559, (1993)

[8]

Agardh E., Torffvit O., Agardh C-D., Putative risk factors associated with retinopathy in patients with diabetes diagnosed at or after 30 years of age, Diabetic Med, 6, pp. 724-727, (1989)

[9]

Klein R., Klein BEK, Moss SE, Davis MD, DeMets DL., The Wisconsin epidemiologic study of diabetic retinopathy. X. Four‐year incidence and progression of diabetic retinopathy when age at diagnosis is 30 years or more, Arch Ophthalmol, 107, pp. 244-249, (1989)

[10]

Nabarro JDN., Diabetes in the United Kingdom: a personal series, Diabetic Med, 8, pp. 59-68, (1991)

← 1 2 →