IRREVERSIBLE DROP OF SYSTEMIC VASCULAR RESISTANCES IN PATIENTS IMPLANTED WITH A JARVIK TOTAL ARTIFICIAL-HEART

被引：4

作者：

DELEUZE, P ^{[1
]}

LOISANCE, DY ^{[1
]}

SHIIYA, N ^{[1
]}

WAN, F ^{[1
]}

HILLION, ML ^{[1
]}

BENVENUTI, C ^{[1
]}

HEURTEMATTE, Y ^{[1
]}

CACHERA, JP ^{[1
]}

机构：

[1] HOP HENRI MONDOR,CNRS,URA 1431,CTR RECH CHIRURG,SERV CHIRURG CARDIOTHORAC,F-94010 CRETEIL,FRANCE

来源：

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS | 1991年 / 14卷 / 05期

关键词：

TOTAL ARTIFICIAL HEART; SYSTEMIC VASCULAR RESISTANCES; MULTIORGAN FAILURE;

D O I：

10.1177/039139889101400508

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Maintenance of the body's perfusion by a total artificial heart (TAH) may result in physiological alterations to the circulatory system. Little has been said about modifications to systemic vascular resistances (SVR) during TAH assistance. This paper reports on two patients implanted with a Jarvik - 70 cc TAH, who died after 1 and 3 days, both with an irreversible drop of SVR related to a complete loss of vascular tone but not related to sepsis. Activation of multiple cascades of inflammation, triggered by the extracorporeal circulation (ECC), is maintained during TAH support. Desperately sick patients might not be able to face the vaso-active situations created by the inflammatory response.

引用

页码：286 / 289

页数：4

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