SYNTHESIS OF OPTICALLY PURE CIS EPOXYALCOHOLS VIA AN ENZYMATIC ROUTE - AN ALTERNATIVE TO THE SHARPLESS ASYMMETRIC EPOXIDATION

被引：41

作者：

GRANDJEAN, D

PALE, P

CHUCHE, J

机构：

[1] Laboratoire de Chimie Orgamque Physique, associé an CNRS, Université de Reims-Champagne-Ardenne, 51100 Reims

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 26期

关键词：

D O I：

10.1016/0040-4039(91)80682-V

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically pure (2S, 3R)-4-butyryloxy-2,3-epoxybutan-1-ol 2b and (2R, 3S)-4-tert-butyldiphenylsilyoxy-2,3-epoxybutan-1-ol 5, starting materials for the synthesis of enantiomeric epoxyalcohols 3 and 4 were obtained after enzymatic hydrolysis of meso cis-2,3-epoxybutane-1,4-diol diesters 1b.

引用

页码：3043 / 3046

页数：4

共 15 条

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