THE RELATIONSHIP OF HUMAN SAPHENOUS-VEIN INTIMAL AREA TO AGE AND GENDER

被引：3

作者：

DAVIES, MG

BROCKBANK, KGM

HAGEN, PO

机构：

[1] Atherosclerosis Research Laboratory, Department of Surgery Duke Univ Medical Center, Durham North Carolina

[2] CryoLife Inc., Marietta

[3] Department of Biochemistry, Duke University Medical Center, Durham, North Carolina

来源：

VASCULAR SURGERY | 1992年 / 26卷 / 09期

关键词：

D O I：

10.1177/153857449202600902

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The saphenous vein is an essential element in arterial bypass surgery. It is known to develop intimal thickening following transplantation to the arterial circulation. No data are available on the relationship of normal saphenous vein intimal area and the age or the gender of the patient. One hundred sixty-two consecutive, donated, cadaveric, midtibial samples of the long saphenous vein were harvested. The donors ranged in age from twelve to eighty-two years; there were 121 males and 41 females. The areas of the intima and media and the intimal ratio (intimal area/[intimal + medial area]) were calculated by computer videomorphometry. There was no correlation between the three variables and age, but there was a significant correlation between the gender of the donor and the intimal area (r2=0.25, p=0.0012) and the intimal ratio (r2=0.34, p=0.0001) showing that females have a greater intimal ares than males. These findings suggest that gender should be considered as a variable in the choke of suitable control values in subsequent human studies on the development of intimal hyperplasia in venous bypass grafts.

引用

页码：700 / 704

页数：5

共 13 条

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