Emergent treatments based on the pathophysiology of bipolar disorder: A selective review

被引：7

作者：

Brady, Roscoe O. ^{[1
,2
]}

Keshavan, Matcheri ^{[1
,2
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Dept Psychiat, Boston, MA 02215 USA

[2] Harvard Med Sch, Dept Psychiat, Boston, MA USA

来源：

ASIAN JOURNAL OF PSYCHIATRY | 2015年 / 18卷

关键词：

Bipolar disorder; TMS; Mania; Depression; Genetics;

D O I：

10.1016/j.ajp.2015.07.017

中图分类号：

R749 [精神病学];

学科分类号：

100205 [精神病与精神卫生学];

摘要：

Bipolar disorder is a chronic psychiatric disorder that is a cause of significant symptomatology even in the setting of optimal treatment. Most current treatments are developed from serendipity, and not based on known pathophysiology. In this review we examine a number of somatic and pharmacologic therapies that are poised to become part of the armamentarium of interventions to treat bipolar illness. As a group, these interventions are derived from a growing understanding of the biological underpinnings of bipolar disorders. We will look at emergent treatments based on our understanding of the molecular biology, neuroanatomy, and the genetics of bipolar disorder. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：15 / 21

页数：7

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