ANTIERYTHROCYTE MEMBRANE ANTIBODIES DETECTED IN SERA OF DOGS NATURALLY INFECTED WITH BABESIA-GIBSONI

被引：30

作者：

ADACHI, K

YOSHIMOTO, A

HASEGAWA, T

SHIMIZU, T

GOTO, Y

MAKIMURA, S

机构：

[1] MIYAZAKI UNIV,FAC AGR,DEPT VET HYG,MIYAZAKI 88921,JAPAN

[2] MIYAZAKI UNIV,FAC AGR,DEPT VET MICROBIOL,MIYAZAKI 88921,JAPAN

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 1992年 / 54卷 / 06期

关键词：

ANTIERYTHROCYTE MEMBRANE ANTIBODY; BABESIA-GIBSONI; DOG; ELISA; IMMUNOBLOTTING;

D O I：

10.1292/jvms.54.1081

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Due to the potential for anti-erythrocyte membrane antibodies as possible enhancers of erythrocyte destruction, the presence of serum anti-erythrocyte membrane antibodies in 31 dogs with Babesia gibsoni infection admitted to a veterinary hospital was investigated by an enzyme linked immunosorbent assay (ELISA) and immunoblotting analyses. This infection resulted in an increase of anti-erythrocyte membrane antibodies in 84% (IgG) and 74% (IgM) of 31 infected dogs, respectively. This was confirmed by the similarity in the protein profiles of the erythrocyte membrane antigens immunoblotted with rabbit antiserum to dog erythrocyte membrane antigens and infected dog serum. These results suggest the production of anti-erythrocyte membrane antibodies was induced by B. gibsoni infection.

引用

页码：1081 / 1084

页数：4

共 17 条

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