AN ACTIVATED SLUDGE-BASED BIOSENSOR FOR RAPID IC(50) ESTIMATION AND ONLINE TOXICITY MONITORING

被引：50

作者：

KONG, Z ^{[1
]}

VANROLLEGHEM, PA ^{[1
]}

VERSTRAETE, W ^{[1
]}

机构：

[1] STATE UNIV GHENT,CTR ENVIRONM SANITAT,MICROBIAL ECOL LAB,COUPURE LINKS 653,B-9000 GHENT,BELGIUM

来源：

BIOSENSORS & BIOELECTRONICS | 1993年 / 8卷 / 01期

关键词：

TOXICITY TEST; RESPIRATION INHIBITION; BIOSENSOR; IC(50);

D O I：

10.1016/0956-5663(93)80043-O

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The RODTOX (Rapid Oxygen Demand and TOXicity tester). an activated sludge-based respirographic biosensor, is a device for on-line monitoring of the short-term biochemical oxygen demand (stBOD) and potential toxicity of incoming wastewater on the basis of on-line interpretation of respirograms resulting from pulse additions of either calibration substrate or sample. The principle of toxicity detection is based on the comparison of calibration respirograms before and after receiving a potential toxicant. In this paper, the results of the RODTOX as an on-line toxicity monitor are presented. In addition, a simple and fast procedure to estimate the IC50 of a toxicant has been developed. and its validity and good repeatability demonstrated. The performance of this procedure is compared with that of the Microtox test.

引用

页码：49 / 58

页数：10

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