OUTCOME OF PARTIAL SPLENECTOMY FOR TYPE-I GAUCHER DISEASE

被引：43

作者：

ZIMRAN, A

ELSTEIN, D

SCHIFFMANN, R

ABRAHAMOV, A

GOLDBERG, M

BARMAOR, JA

BRADY, RO

GUZZETTA, PC

BARTON, NW

机构：

[1] SHAARE ZEDEK MED CTR, DEPT SURG A, IL-91031 JERUSALEM, ISRAEL

[2] RAMBAM MED CTR, DEPT PEDIAT SURG, HAIFA, ISRAEL

[3] NATL INST HLTH, DEV & METAB NEUROL BRANCH, BETHESDA, MD USA

[4] UNIV TEXAS, SW MED CTR, DIV PEDIAT SURG, DALLAS, TX 75235 USA

来源：

JOURNAL OF PEDIATRICS | 1995年 / 126卷 / 04期

关键词：

D O I：

10.1016/S0022-3476(95)70358-6

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Partial splenectomy was introduced to achieve the benefits of splenectomy and to avoid the risk of overwhelming infection in patients with symptomatic Gaucher disease. We observed regrowth of the splenic remnant, reemergence of preoperative symptoms, and new bone involvement among most of our patients who had undergone partial splenectomy. Enzyme replacement therapy has markedly limited indications for splenectomy, partial or total, for Gaucher disease.

引用

页码：596 / 597

页数：2

共 8 条

[1] REPLACEMENT THERAPY FOR INHERITED ENZYME DEFICIENCY - MACROPHAGE-TARGETED GLUCOCEREBROSIDASE FOR GAUCHERS-DISEASE [J].