DISRUPTION OF N-LINKED GLYCOSYLATION OF BOVINE LUTEINIZING-HORMONE BETA-SUBUNIT BY SITE-DIRECTED MUTAGENESIS DRAMATICALLY INCREASES ITS INTRACELLULAR STABILITY BUT DOES NOT AFFECT BIOLOGICAL-ACTIVITY OF THE SECRETED HETERODIMER

被引:36
作者
KAETZEL, DM [1 ]
VIRGIN, JB [1 ]
CLAY, CM [1 ]
NILSON, JH [1 ]
机构
[1] CASE WESTERN RESERVE UNIV,SCH MED,DEPT PHARMACOL,CLEVELAND,OH 44106
关键词
D O I
10.1210/mend-3-11-1765
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
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页码:1765 / 1774
页数:10
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