AN EFFICIENT PROCEDURE FOR SOLID-PHASE SYNTHESIS OF PHOSPHOPEPTIDES BY THE FMOC STRATEGY

被引:88
作者
WAKAMIYA, T
SARUTA, K
YASUOKA, J
KUSUMOTO, S
机构
关键词
D O I
10.1246/cl.1994.1099
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The Fmoc-mode solid-phase method was successfully applied to establish a practical procedure for the synthesis of phosphopeptides. Both Fmoc-phosphoserine with free phosphoric moiety and its monobenzyl phosphate derivative were examined as one of starting materials for the synthesis of peptides. The employment of the latter gave better result in respects of the yield and purity of the product than that obtained with the former.
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页码:1099 / 1102
页数:4
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