WEGENERS GRANULOMATOSIS - OBSERVATIONS ON TREATMENT WITH ANTIMICROBIAL AGENTS

被引：254

作者：

DEREMEE, RA

MCDONALD, TJ

WEILAND, LH

机构：

[1] MAYO CLIN & MAYO FDN, DIV THORAC DIS & INTERNAL MED, ROCHESTER, MN 55901 USA

[2] MAYO CLIN & MAYO FDN, DEPT OTORHINOLARYNGOL, ROCHESTER, MN 55901 USA

[3] MAYO CLIN & MAYO FDN, DEPT PATHOL, ROCHESTER, MN 55901 USA

来源：

MAYO CLINIC PROCEEDINGS | 1985年 / 60卷 / 01期

关键词：

D O I：

10.1016/S0025-6196(12)65279-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients (12) with Wegener''s granulomatosis were treated with antimicrobial agents, chiefly trimethoprimsulfamethoxazole. The clinical course improved in 11 of the 12 patients who received this treatment. The success of antimicrobial treatment suggests the possibility of a microbial infection as the inciting cause of Wegener''s granulomatosis in some patients. Alternatively, these agemts im particular, trimethoprim-sulfamethoxazole may posses immumnosuppressant activity.

引用

页码：27 / 32

页数：6

共 5 条

[1] DEREMEE RA, 1976, MAYO CLIN PROC, V51, P777
[2] SPECTRUM OF VASCULITIS - CLINICAL, PATHOLOGIC, IMMUNOLOGICAL, AND THERAPEUTIC CONSIDERATIONS
FAUCI, AS
HAYNES, BF
KATZ, P
[J]. ANNALS OF INTERNAL MEDICINE, 1978, 89 (05) : 660 - 676
[3] WEGENERS GRANULOMATOSIS - PROSPECTIVE CLINICAL AND THERAPEUTIC EXPERIENCE WITH 85 PATIENTS FOR 21 YEARS
FAUCI, AS
HAYNES, BF
KATZ, P
WOLFF, SM
[J]. ANNALS OF INTERNAL MEDICINE, 1983, 98 (01) : 76 - 85
[4] RELAPSES IN WEGENERS GRANULOMATOSIS - THE ROLE OF INFECTION
PINCHING, AJ
REES, AJ
PUSSELL, BA
LOCKWOOD, CM
MITCHISON, RS
PETERS, DK
[J]. BRITISH MEDICAL JOURNAL, 1980, 281 (6244) : 836 - 838
[5] WORMSER GP, 1979, ANN INTERN MED, V91, P420, DOI 10.7326/0003-4819-91-3-420

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