POSITION-EFFECT VARIEGATION AND THE NEW BIOLOGY OF HETEROCHROMATIN

被引：219

作者：

KARPEN, GH

机构：

[1] Molecular Biology and Virology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037-1099

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(05)80055-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The phenomenon of position-effect variegation has long been used as evidence for the importance of chromosome position to gene expression in eukaryotes. Investigations published within the past few years demonstrate that position-effect variegation is caused by multiple mechanisms, and that direct tests of hypotheses are possible with numerous model systems.

引用

页码：281 / 291

页数：11

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