5H-2-PYRINDINES FROM 2-BROMOCYCLOPENTENE-1-CARBOXALDEHYDE

被引：15

作者：

GILCHRIST, TL ^{[1
]}

KEMMITT, PD ^{[1
]}

GERMAIN, AL ^{[1
]}

机构：

[1] GLAXO WELLCOME,DARTFORD DA1 5AH,KENT,ENGLAND

来源：

TETRAHEDRON | 1995年 / 51卷 / 33期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0040-4020(95)00509-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium(0) catalysed coupling of 2-bromocyclopentene-1-carboxaldehyde N,N'-dimethylhydrazone 1 with vinylzinc halides and with 2-furyl- and 2-thienylzinc halides provides a route to the corresponding 2-vinyl- and 2-heteroaryl-cyclopentene-1-carboxaldehyde dimethylhydrazones. These cyclise thermally to 6,7-dihydro-5H-2-pyrindines (e.g., 3).

引用

页码：9119 / 9126

页数：8

共 7 条

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