DESIGN OF POTENT CYCLIC GONADOTROPIN-RELEASING HORMONE ANTAGONISTS

被引：39

作者：

RIVIER, J

KUPRYSZEWSKI, G

VARGA, J

PORTER, J

RIVIER, C

PERRIN, M

HAGLER, A

STRUTHERS, S

CORRIGAN, A

VALE, W

机构：

[1] AGOURON INST,LA JOLLA,CA 92037

[2] BACHEM LABS,TORRANCE,CA 90505

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 03期

关键词：

D O I：

10.1021/jm00398a030

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：677 / 682

页数：6

相关论文

共 26 条

[1] NUCLEAR-MAGNETIC-RESONANCE ANALYSIS AND CONFORMATIONAL CHARACTERIZATION OF A CYCLIC DECAPEPTIDE ANTAGONIST OF GONADOTROPIN-RELEASING-HORMONE [J].

BANIAK, EL ;

RIVIER, JE ;

STRUTHERS, RS ;

HAGLER, AT ;

GIERASCH, LM .

BIOCHEMISTRY, 1987, 26 (09) :2642-2656

[2]

BANIAK EL, 1988, PEPTIDES CHEM BIOL

[3]

CORBIN A, 1975, ENDOCR RES COMMUN, V2, P1

[4] TISSUE SULFHYDRYL GROUPS [J].

ELLMAN, GL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) :70-77

[5]

HOEGER C, 1987, Biochromatography, V2, P134

[6]

HOOK WA, 1985, FED PROC, V44, P1323

[7] GONADOTROPIN-RELEASING-HORMONE ANALOG DESIGN - STRUCTURE-FUNCTION STUDIES TOWARD THE DEVELOPMENT OF AGONISTS AND ANTAGONISTS - RATIONALE AND PERSPECTIVE [J].

KARTEN, MJ ;

RIVIER, JE .

ENDOCRINE REVIEWS, 1986, 7 (01) :44-66

[8]

KARTEN MJ, 1987, LHRH ITS ANALOGS C 2, P179

[9] PEPTIDE SWEETENERS .3. EFFECT OF MODIFYING THE PEPTIDE-BOND ON THE SWEET TASTE OF L-ASPARTYL-L-PHENYLALANINE METHYL-ESTER AND ITS ANALOGS [J].

MACDONALD, SA ;

WILLSON, CG ;

CHOREV, M ;

VERNACCHIA, FS ;

GOODMAN, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (04) :413-420

[10]

MARKI W, 1981, J AM CHEM SOC, V103, P3178