OPTIMIZATION OF INORGANIC CAPILLARY ELECTROPHORESIS FOR THE ANALYSIS OF ANIONIC SOLUTES IN REAL SAMPLES

Inorganic capillary electrophoresis (ICE) is a separation technique which offers many advantages for the analysis of anionic solutes in real samples. Parameters which influence ICE separations such as system configuration, choice of electrolyte anion, electrolyte pH and the addition of electroosmotic flow modifier were investigated and a number of electrolytes of varying mobilities were studied. Optimized conditions were established for the separation of inorganic anions, organic acids and alkylsulfonates and the technique was applied to the analysis of a variety of anionic solutes in several complex sample matrices.