SELECTIVE IMMUNOSUPPRESSION

被引：2

作者：

ADORINI, L

GUERY, JC

RODRIGUEZTARDUCHY, G

TREMBLEAU, S

机构：

[1] I-20132 Milano

[2] J-C. Gué, I-20132 Milano

[3] I-20132 Milano

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1993年 / 14卷 / 05期

关键词：

D O I：

10.1016/0165-6147(93)90205-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Experimental models of autoimmune diseases have demonstrated that such disease can be prevented or treated by selectively interfering with activation of any of these cell types: antigen-presenting cells, autoreactive T cells and regulatory T cells. Luciano Adorini and colleagues discuss these approaches to selective immunosuppression and examine how similar strategies may become applicable to the treatment of human autoimmune diseases.

引用

页码：178 / 182

页数：5

共 60 条

[1] LIMITED HETEROGENEITY OF T-CELL RECEPTORS FROM LYMPHOCYTES MEDIATING AUTOIMMUNE ENCEPHALOMYELITIS ALLOWS SPECIFIC IMMUNE INTERVENTION [J].

ACHAORBEA, H ;

MITCHELL, DJ ;

TIMMERMANN, L ;

WRAITH, DC ;

TAUSCH, GS ;

WALDOR, MK ;

ZAMVIL, SS ;

MCDEVITT, HO ;

STEINMAN, L .

CELL, 1988, 54 (02) :263-273

[2] NEW PERSPECTIVES ON IMMUNOINTERVENTION IN AUTOIMMUNE-DISEASES [J].

ADORINI, L ;

BARNABA, V ;

BONA, C ;

CELADA, F ;

LANZAVECCHIA, A ;

SERCARZ, E ;

SUCIUFOCA, N ;

WEKERLE, H .

IMMUNOLOGY TODAY, 1990, 11 (11) :383-386

[3]

ADORINI L, 1992, SPRINGER SEMIN IMMUN, V14, P187

[4]

ADORINI L, 1990, INT REV IMMUNOL, V6, P1

[5] IMMUNOMODULATION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS BY ANTIBODIES TO THE ANTIGEN-IA COMPLEX [J].

AHARONI, R ;

TEITELBAUM, D ;

ARNON, R ;

PURI, J .

NATURE, 1991, 351 (6322) :147-150

[6]

ALEXANDER J, 1993, J IMMUNOL, V150, P1

[7] ANTIGENIC-COMPETITION AT THE LEVEL OF PEPTIDE-IA BINDING [J].

BABBITT, BP ;

MATSUEDA, G ;

HABER, E ;

UNANUE, ER ;

ALLEN, PM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (12) :4509-4513

[8] STRUCTURE OF THE HUMAN CLASS-I HISTOCOMPATIBILITY ANTIGEN, HLA-A2 [J].

BJORKMAN, PJ ;

SAPER, MA ;

SAMRAOUI, B ;

BENNETT, WS ;

STROMINGER, JL ;

WILEY, DC .

NATURE, 1987, 329 (6139) :506-512

[9]

BROSTOFF SW, 1984, J IMMUNOL, V133, P1938

[10] PREDOMINANT NATURALLY PROCESSED PEPTIDES BOUND TO HLA-DR1 ARE DERIVED FROM MHC-RELATED MOLECULES AND ARE HETEROGENEOUS IN SIZE [J].

CHICZ, RM ;

URBAN, RG ;

LANE, WS ;

GORGA, JC ;

STERN, LJ ;

VIGNALI, DAA ;

STROMINGER, JL .

NATURE, 1992, 358 (6389) :764-768

← 1 2 3 4 5 6 →