SYNTHETIC STUDIES OF SESQUITERPENES WITH A CIS-FUSED DECALIN SYSTEM .5. A SYNTHETIC APPROACH TO THE STUDY OF STRUCTURE-ACTIVITY-RELATIONSHIPS OF THE TERMITICIDAL NORSESQUITERPENOIDS, CHAMAECYNONE AND RELATED-COMPOUNDS
[2] SUMITOMO CHEM CO LTD,AGR CHEM RES LAB,TAKARAZUKA,HYOGO 665,JAPAN
来源:
JOURNAL OF NATURAL PRODUCTS
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1994年
/
57卷
/
07期
关键词:
D O I:
10.1021/np50109a008
中图分类号:
Q94 [植物学];
学科分类号:
071001 ;
摘要:
Various analogues of chamaecynone [1] were prepared from alpha-santonin, and the termiticidal activity of these compounds was examined. All compounds possessing a 5 beta H-13-noreudesmane skeleton with a ethynyl group at C-7 showed significant termiticidal activity. Changes in the structure of the A-ring of these compounds also influenced the potency of their termiticidal activity.