BACTERIAL PROTEIN TRANSLOCATION - KINETIC AND THERMODYNAMIC ROLE OF ATP AND THE PROTONMOTIVE FORCE

被引：52

作者：

DRIESSEN, AJM

机构：

[1] Department of Microbiology, University of Groningen, 9751 NN Haren

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 06期

关键词：

D O I：

10.1016/0968-0004(92)90381-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The energetic mechanism of preprotein export in Escherichia coli has been a source of controversy for many years. In vitro studies of translocation reactions that use purified soluble and membrane components have now clarified the main features of this mechanism. Translocation occurs through consecutive steps which each have distinct energy requirements. Initiation of translocation requires ATP and the SecA protein. Most of the further steps can be driven by the protonmotive force (DELTA-p).

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页码：219 / 223

页数：5

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