INVESTIGATION OF THE ENANTIOMERIZATION BARRIER OF HOMOFURAN BY COMPUTER-SIMULATION OF INTERCONVERSION PROFILES OBTAINED BY COMPLEXATION GAS-CHROMATOGRAPHY

被引：46

作者：

SCHURIG, V ^{[1
]}

JUNG, M ^{[1
]}

SCHLEIMER, M ^{[1
]}

KLARNER, FG ^{[1
]}

机构：

[1] RUHR UNIV BOCHUM,FAK CHEM,W-4630 BOCHUM 1,GERMANY

来源：

CHEMISCHE BERICHTE-RECUEIL | 1992年 / 125卷 / 05期

关键词：

ENANTIOMERIZATION; DYNAMIC COMPLEXATION GAS CHROMATOGRAPHY; HOMOFURAN;

D O I：

10.1002/cber.19921250543

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

By computer simulation of experimental interconversion profiles, obtained by complexation gas chromatography, rate constants of enantiomerization have been determined for homofuran between 95 and 130-degrees-C. Since enantiomerization proceeds at similar rates in the mobile and stationary phase, the rate constants obtained by an Arrhenius plot are in excellent agreement with values determined independently by polarimetry between 60 and 90-degrees-C. We thus demonstrate that dynamic chromatography can be an easy means for the rapid determination of enantiomerization (or isomerization) barriers of ca. 70-120 kJ mol-1 requiring only minute amounts of racemic sample.

引用

页码：1301 / 1303

页数：3

共 16 条

[1]

[Anonymous], ANGEW CHEM

[2] DYNAMIC PHENOMENA DURING ENANTIOMER RESOLUTION BY COMPLEXATION GAS-CHROMATOGRAPHY - A KINETIC-STUDY OF ENANTIOMERIZATION [J].