SUPERIOR HEMODYNAMICS IN LEFT HEART BYPASS WITHOUT SYSTEMIC HEPARINIZATION

被引：21

作者：

VONSEGESSER, LK

WEISS, BM

GALLINO, A

LESKOSEK, B

REDHA, F

VONFELTEN, A

TURINA, M

机构：

[1] Department of Surgery, Zurich

[2] Institute of Anesthesiology, Zurich

[3] Department of Medicine, University Hospital, Zurich

[4] Klinik für Herzgefäßchirurgie, Universitätsspital, Zürich, CH-8091

来源：

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | 1990年 / 4卷 / 07期

关键词：

Hemodynamics in left heart bypass; Heparin surface coating; Heparinless perfusion; Left heart bypass; Mechanical circulatory support;

D O I：

10.1016/1010-7940(90)90047-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Open-chest left heart bypass was performed in 10 canine experiments (30–9 kg) by a servo controlled roller pump for 6 h at a pump flow of 50ml/min per kg body weight. The surfaces of the tubing sets were either standard (with systemic heparinization) or with end-point attached heparin(no systemic heparin). Besides continuous monitoring of hemodynamics, a standard battery of blood samples was taken before bypass, after 10 min and every hour there after. There is no evidence of increased fibrin production in the group with end-point attached heparin surfaces perfused without systemic heparinization. Superior hemodynamics in left heart bypass performed without systemic heparinization appear to be due to improved hemostasis, reduced blood loss and therefore reduced transfusion requirements. Left heart bypass with heparin-coated equipment has been successfully used for resection of a thoracoabdominal aneurysm in six patients. © Springer-Verlag.

引用

页码：384 / 389

页数：6

共 7 条

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