2 NEW EXTRACELLULAR SERINE PROTEASES FROM STREPTOMYCES-FRADIAE

被引：21

作者：

SINHA, U ^{[1
]}

WOLZ, SA ^{[1
]}

LAD, PJ ^{[1
]}

机构：

[1] GENENCOR INC,180 KIMBALL WAY,S SAN FRANCISCO,CA 94080

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1991年 / 23卷 / 10期

关键词：

D O I：

10.1016/0020-711X(91)90133-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Two new extracellular serine proteases have been purified to homogeneity from Streptomyces fradiae. 2. On amino acid sequencing, striking homology is observed between the first enzyme and Streptomyces griseus Protease A, and the second enzyme and S. griseus trypsin. 3. The sequence information shows for the first time that structurally and enzymatically related serine proteases are extracellularly expressed by different Streptomycetes. 4. Differential keratinolytic substrate specificity among these two microbes are probably due to a difference in disulfide reduction capacity.

引用

页码：979 / 984

页数：6

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