HIGH ENDOTHELIAL VENULES (HEVS) - SPECIALIZED ENDOTHELIUM FOR LYMPHOCYTE MIGRATION

被引：443

作者：

GIRARD, JP

SPRINGER, TA

机构：

[1] HARVARD UNIV, SCH MED, CTR BLOOD RES, BOSTON, MA 02115 USA

[2] HARVARD UNIV, SCH MED, DEPT PATHOL, BOSTON, MA 02115 USA

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 09期

关键词：

D O I：

10.1016/0167-5699(95)80023-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

High endothelial venules (HEVs) are specialized postcapillary venules found in lymphoid tissues that support high levels of lymphocyte extra-vasation from the blood. Here, Jean-Philippe Girard and Timothy Springer highlight the unique properties of HEV endothelium, discuss the molecular mechanisms controlling HEV specialization and review evidence suggesting that HEVs could play an important role in the pathogenesis of chronic inflammatory diseases.

引用

页码：449 / 457

页数：9

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