INHALATION OF NITRIC-OXIDE AS A TREATMENT OF PULMONARY-HYPERTENSION IN CONGENITAL DIAPHRAGMATIC-HERNIA

被引：31

作者：

HENNEBERG, SW ^{[1
]}

JEPSEN, S ^{[1
]}

ANDERSEN, PK ^{[1
]}

PEDERSEN, SA ^{[1
]}

机构：

[1] ODENSE UNIV HOSP,DEPT SURG,DK-5000 ODENSE C,DENMARK

来源：

JOURNAL OF PEDIATRIC SURGERY | 1995年 / 30卷 / 06期

关键词：

CONGENITAL DIAPHRAGMATIC HERNIA; PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN; NITRIC OXIDE;

D O I：

10.1016/0022-3468(95)90763-7

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Congenital diaphragmatic hernia (CDH) still has a mortality risk of around 40%. The concomitant pulmonary hypoplasia and the persistent pulmonary hypertension are of major prognostic importance. The use of a selective pulmonary vasodilator may revert this vicious circle that is fatal to many children. Inhalation of nitric oxide (NO) hai been suggested as a rational treatment of this condition. The authors report three cases of high-risk infants with CDH where NO was used successfully. It is concluded that hypoxemia in CDH can be treated successfully with NO inhalation when conventional treatment fails, and it may in some cases prove to be an alternative to ECMO. Copyright (C) 1995 by W.B. Saunders company

引用

页码：853 / 855

页数：3

共 22 条

[1] PERSISTENT PULMONARY-HYPERTENSION IN HIGH-RISK CONGENITAL DIAPHRAGMATIC-HERNIA PATIENTS - INCIDENCE AND VASODILATOR THERAPY [J].