RELATIVE SENSITIVITY OF BLOOD AND BONE-MARROW CULTURES IN TYPHOID-FEVER

被引：26

作者：

AKOH, JA

机构：

[1] Ahmadu Bello University Teaching Hospital, Zaria

来源：

TROPICAL DOCTOR | 1991年 / 21卷 / 04期

关键词：

D O I：

10.1177/004947559102100415

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In a prospective study of typhoid fever in Ahmadu Bello University Hospital, Zaria, the relative diagnostic sensitivities of blood culture and bone marrow culture were studied. The results in 64 patients with proved diagnosis of typhoid fever (either by recovery of S. typhi from stool, blood and/or bone marrow or by a positive Widal agglutination test) are presented. Forty-four per cent and 59% of the patients yielded S. typhi on blood and bone marrow cultures, respectively. In 31 patients who were investigated by both blood and bone marrow cultures, the yields of S. typhi were 35% and 61% respectively. This difference is statistically significant (P < 0.05). In this study bone marrow culture proved to be the most sensitive diagnostic test for typhoid fever. A simple technique of bone marrow aspiration is described and its use is recommended for large general teaching hospitals.

引用

页码：174 / 176

页数：3

共 10 条

[1]

Olurin E.O., Ajayi O.O., Bohrer S.P., Typhoid perforations, J R Coll Surg Edinb, pp. 353-363, (1972)

[2]

Klotz S.A., Jorgensen J.H., Buckwold F.J., Craven P.C., Typhoid fever: an epidemic with remarkably few clinical signs and symptoms, Arch Intern Med, pp. 533-537, (1984)

[3]

Wintrobe M.M., Clinical haematology, pp. 29-45, (1967)

[4]

Dacie J.V., Lewis S.M., Basic haematological techniques, Practical haematology, pp. 21-67, (1975)

[5]

Hirsowitz L., Cassel R., Sternal marrow cultures in typhoid fever, BMJ, pp. 862-873, (1951)

[6]

Huckstep R.L., Recent advances in the surgery of typhoid fever, Ann R Coll Surg Engl, pp. 207-230, (1960)

[7]

Piaggio-Blanco R.A., Paseyro P., San-Guinetti CM. Cultivation of bone marrow as a diagnostic method in typhoid fever (Abstract), Bull Hyg, (1943)

[8]

Robertson R.P., Wahab M.F.A., Raasch F.O., Evaluation of chloramphenicol and ampicillin in Salmonella enteric fever, N Engl J Med, pp. 171-176, (1968)

[9]

Gillman R.H., Terminel M., Levine M.M., Hernendez-Mendoza P., Hornick R.B., Relative efficacy of blood, urine, rectal swab, bone marrow and rose spot cultures for recovery of Salmonella typhi in typhoid fever, Lancet, pp. 1211-1213, (1975)

[10]

Farooqui B.J., Khurshid M., Ashfaq M.K., Comparative yield of Salmonella typhi from blood and bone marrow cultures in patients with fever of unknown origin, J Clin Pathol, pp. 258-259, (1991)

← 1 →