CHARACTERIZATION OF THE ENDOGENOUS NONECOTROPIC MURINE LEUKEMIA VIRUSES OF NZB/B1NJ AND SM/J INBRED STRAINS

被引：51

作者：

FRANKEL, WN

LEE, BK

STOYE, JP

COFFIN, JM

EICHER, EM

机构：

[1] JACKSON LAB,BAR HARBOR,ME 04609

[2] TUFTS UNIV,SCH MED,DEPT MOLEC BIOL,BOSTON,MA 02111

来源：

MAMMALIAN GENOME | 1992年 / 2卷 / 02期

关键词：

D O I：

10.1007/BF00353859

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We characterized 84 endogenous nonecotropic proviruses of NZB/BlNJ and SM/J inbred strains by examining proviral junction fragment segregation in recombinant inbred (RI) and backcross mice. Forty-five proviruses were shared with other laboratory strains, but 28 were unique to NZB/BlNJ or SM/J. Proviral loci were located on 17 of the 19 mouse autosomes and on both sex chromosomes. These markers will facilitate gene mapping in the NXSM RI set and contribute to the pursuit of a more complete map of the mouse genome.

引用

页码：110 / 122

页数：13

共 33 条

[1]

ANN DK, 1985, J BIOL CHEM, V260, P5863

[2] ISOLATION AND ANALYSIS OF THE MOUSE OPSIN GENE [J].