CONTROL OF ENANTIOFACIAL DIFFERENTIATION IN THE ADDITION-REACTION OF ORGANOMETALLICS TO A NITRONE IN THE PRESENCE OF AN EXTERNAL CHIRAL AUXILIARY

被引：37

作者：

UKAJI, Y

HATANAKA, T

AHMED, A

INOMATA, K

机构：

来源：

CHEMISTRY LETTERS | 1993年 / 08期

关键词：

D O I：

10.1246/cl.1993.1313

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It was observed that differentiation of enantiotopic face in the addition reaction of organometallics to 3,4-dihydroisoquinoline N-oxide was well-regulated by the use of an external chiral auxiliary; i.e., Grignard reagents added from the si-face of the nitrone in the presence of bromomagnesium (2S,3R)-4-dimethylamino-1,2-diphenyl-3-methyl-2-butoxide, while dialkylzinc attacked from the re-face.

引用

页码：1313 / 1316

页数：4

共 19 条

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