Application of the mobile order thermodynamics to predict the solubility of solid hydrocarbons in pure solvents and nonpolar binary solvent systems.

This work extends the application of the thermodynamics of mobile order from the solubility prediction in single solvents to that in binary solvent blends without additional new parameters. Predicted solubilities are compared to the experimental values for solid n-octadedane, n-nonadecane and naphthalene in various non-polar, polar and hydrogen-bonded pure solvents as well as in 22 two-component solvent systems involving only non-specific interactions. Absolute average deviations between predicted and experimental results do not exceed 10 % in single solvents and 5 % in binary mixtures. The solubility profiles versus solvent composition show that the solubilities are additive in mixtures of solvents whose interaction characteristics are very similar.