C-MYC DETECTION IN BONE-MARROW BIOPSIES

被引：18

作者：

PAVELIC, K

PAVELIC, ZP

PREISLER, HD

机构：

[1] UNIV CINCINNATI, COLL MED, BARRETT CTR CANC PREVENT, CINCINNATI, OH 45267 USA

[2] RUDJER BOSKOVIC INST, DEPT EXPTL BIOL & MED, YU-41000 ZAGREB, CROATIA

来源：

LEUKEMIA RESEARCH | 1991年 / 15卷 / 11期

关键词：

PROTOONCOGENE; C-MYC; BONE MARROW;

D O I：

10.1016/0145-2126(91)90114-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the past the fixation procedures employed in the immunohistostaining of paraffin-embedded tissues with anti-myc protein antibodies were unsatisfactory since they permitted the leakage of the protein from its normal nuclear localization in the cell. In the studies described here 3 different fixation methods were compared and it was shown that only one, the AMeX method, was suitable for studying c-myc expression in bone marrow biopsies.

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收藏

页码：1075 / 1078

页数：4

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