MULTIPLE GENES FOR G-PROTEIN-COUPLED RECEPTORS AND THEIR EXPRESSION IN LINGUAL EPITHELIA

被引：45

作者：

ABE, K

KUSAKABE, Y

TANEMURA, K

EMORI, Y

ARAI, S

机构：

[1] UNIV TOKYO,FAC AGR,DEPT AGR CHEM,BUNKYO KU,TOKYO 113,JAPAN

[2] UNIV TOKYO,FAC AGR,DEPT VET ANAT,BUNKYO KU,TOKYO 113,JAPAN

[3] UNIV TOKYO,FAC SCI,DEPT BIOPHYS & BIOCHEM,BUNKYO KU,TOKYO 113,JAPAN

来源：

FEBS LETTERS | 1993年 / 316卷 / 03期

关键词：

TASTE RECEPTOR; G-PROTEIN-COUPLED RECEPTOR; LINGUAL EPITHELIUM; POLYMERASE CHAIN REACTION;

D O I：

10.1016/0014-5793(93)81302-G

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein-coupled seven-transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.

引用

页码：253 / 256

页数：4

共 21 条

[1] A BITTER SUBSTANCE INDUCES A RISE IN INTRACELLULAR CALCIUM IN A SUBPOPULATION OF RAT TASTE CELLS [J].