CHEMICAL SIGNALING IN THE BRAIN

被引：21

作者：

CHANGEUX, JP ^{[1
]}

机构：

[1] COLL FRANCE,F-75231 PARIS 05,FRANCE

来源：

SCIENTIFIC AMERICAN | 1993年 / 269卷 / 05期

关键词：

D O I：

10.1038/scientificamerican1193-58

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Every thought, every voluntary action, begins when a neurotransmitter, released into a synapse, locks with its corresponding receptor. The receptor changes shape, causing the neuron to become permeable to ions. As the ions move, they change the electrical potential of the cell, causing a wave of current to run down it. How binding to a receptor can induce ionic flow is now becoming clear.

引用

页码：58 / &

共 5 条

[1] THE FUNCTIONAL ARCHITECTURE OF THE ACETYLCHOLINE NICOTINIC RECEPTOR EXPLORED BY AFFINITY LABELING AND SITE-DIRECTED MUTAGENESIS
CHANGEUX, JP
GALZI, JL
DEVILLERSTHIERY, A
BERTRAND, D
[J]. QUARTERLY REVIEWS OF BIOPHYSICS, 1992, 25 (04) : 395 - 432
[2] CHANGEUX JP, 1985, NEURONAL MAN BIOL MI
[3] CHANGEUX JP, 1990, FIDIA RES F NEUROSCI, V4
[4] KARLIN A, 1991, HARVEY LECT, V85, P71
[5] NICOTINIC ACETYLCHOLINE-RECEPTOR AT 9-ANGSTROM RESOLUTION
UNWIN, N
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1993, 229 (04) : 1101 - 1124

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