A CASE OF SJOGRENS-SYNDROME COMPLICATING IMMUNE-MEDIATED APLASTIC-ANEMIA

被引：5

作者：

SATOH, M

YAMAGATA, H

WATANABE, F

MATSUSHITA, Y

NAKAYAMA, S

MURAKAMI, M

MATSUYAMA, J

OSHIMA, S

AKIZUKI, M

机构：

[1] School of Medicine, Department of Medicine, Division of Rheumatology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, 27599-7280, N.C.

[2] Department of Laboratory Medicine, National Murayama Hospital

[3] Department of Medicine, Keio University School of Medicine, Tokyo

来源：

CLINICAL RHEUMATOLOGY | 1993年 / 12卷 / 02期

关键词：

APLASTIC ANEMIA; SJOGRENS SYNDROME; ANTI-SSA/RO ANTIBODIES; ANTI-SSB/LA ANTIBODIES; ANTINUCLEAR ANTIBODIES; BONE MARROW STEM CELL CLONAL ASSAY;

D O I：

10.1007/BF02231538

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 78-year-old Japanese woman with Sjogren's syndrome complicating immune-mediated aplastic anaemia is described. A diagnosis of aplastic anaemia was made from severe pancytopenia with hypoplastic marrow. Laboratory studies suggested an association of bone marrow suppressive T-lymphocytes with the pathogenesis of aplastic anaemia. Following the administration of mepithiostan and prednisolone, pancytopenia improved gradually. Two years after the onset of aplastic anaemia, Raynaud's phenomenon developed and examinations revealed the existence of keratoconjunctivitis sicca and anti-SSA/Ro and anti-SSB/La antibodies.

引用

页码：257 / 260

页数：4

共 14 条

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