AGRIN AND THE MOLECULAR CHOREOGRAPHY OF SYNAPSE FORMATION

被引：64

作者：

NASTUK, MA

FALLON, JR

机构：

[1] Neurobiology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545

来源：

TRENDS IN NEUROSCIENCES | 1993年 / 16卷 / 02期

关键词：

D O I：

10.1016/0166-2236(93)90020-M

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

High concentrations of neurotransmitter receptors characterize neuromuscular junctions as well as neuron-neuron synapses in the brain and periphery. Synaptic function is critically dependent upon this marshalling of neurotransmitter receptors to the post-synaptic membrane. This review discusses agrin's role in orchestrating the molecular topography of the post-synaptic apparatus at nerve-muscle synapses and the emerging evidence suggesting a role for agrin in synaptogenesis in the brain.

引用

页码：72 / 76

页数：5

共 43 条

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