THE USE OF ANGIOTENSIN CONVERTING ENZYME-INHIBITORS IN COMBINATION WITH OTHER ANTIHYPERTENSIVE AGENTS

被引：14

作者：

PICKERING, TG

机构：

[1] Cardiovascular Center, The New York Hospital Cornell Medical Center, New York

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1991年 / 4卷 / 01期

关键词：

ANGIOTENSIN CONVERTING ENZYME INHIBITION; HYPERTENSION; COMBINATION THERAPY; RENIN ANGIOTENSIN SYSTEM;

D O I：

10.1093/ajh/4.1.73S

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Angiotensin converting enzyme (ACE) inhibitors have additive effects with most other antihypertensive agents, but the mechanisms of these interactions vary. With diuretics the interaction with ACE inhibitors can be explained by their contrasting effects on the renin-angiotensin system, while with calcium antagonists it may be attributed to independent mechanisms of action. With beta-blockers there is a variable additive effect, which has been proposed to be due to more complete blockade of the renin-angiotensin system than can be obtained with either type of agent alone.

引用

页码：S73 / S78

页数：6

共 46 条

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